While overstimulation of the CB1 receptor may lead to symptoms such as high blood pressure and abnormally high cholesterol levels, CBD is a CB1 antagonist, so it is not likely to cause such issues. Furthermore, the World Health Organization has recently issued a global report on CBD, claiming that it has a good safety profile and minimal adverse public health effects. 

As previously mentioned, CBD and other cannabinoids affect the endocannabinoid system in the body. This system plays a significant role in regulating numerous physiological processes in the body. One of its most vital actions is helping the body to maintain balance. When someone is overweight, generally speaking, it’s not all about overeating or gluttony, but a combination of functions within the human body that are not functioning correctly. Many holistic doctors will agree that our Western diet and the way we treat disease both play a significant role in creating weight gain

The increased activity of the pancreas in an attempt to secrete additional insulin can cause inflammation throughout the gland. That chronic inflammation can actually destroy the beta cells which are the sites that secrete insulin. This downward spiral diminishes the body’s ability to make insulin at all – a dangerous path that can lead to diabetes.


He did exhaustive research. He found there’d been decades of scientific studies on the effects of THC and CBD on cells and animals, but few trials with humans, because the FDA classifies cannabis and all its components as Schedule 1 drugs, which have “no accepted medical treatment use.” It took Sue Sisley, an Arizona physician, seven years of struggling with bureaucratic hurdles before she received the first FDA approval for a study, just beginning, of marijuana with vets who have PTSD.
Scam CBD sellers tend to manufacture low-grade oils via ethanol (or other solvent-based) extraction, in what is little better than trying to do it yourself in your basement. The result is a liquid that contains a little CBD (along with some other cannabinoids and terpenes), but not in the quantities needed to be effective in terms of any legitimate medicinal function. Moreover, these solvent-based extracts can contain unnecessary and potentially harmful components.
I asked if he knew why CBD is so broadly effective. Could it be a gigantic, all-purpose placebo? He shook his head. His theory is that it’s an essential nutrient, like vitamins and amino acids, and when there’s a deficiency of CBD, people get sick. Because CBD brings the body into homeostasis, or balance, it can work in two directions: cutting appetite in people who over-eat, and increasing appetite in those who need to eat more.

During a day at his office, I saw three patients who’d had success with CBD. The first was Sawyer Maddox, five, from Atlanta, who’d been diagnosed at three with a rare form of epilepsy, Doose Syndrome, which is resistant to medication. He was having more than 200 seizures a day, where he’d drop face first on the floor. His parents fitted him with a catcher’s mask for protection, and carpeted their home with foam to cushion his falls. The pediatric neurologist they saw in Atlanta gave him meds that made things worse. Desperate, the Maddoxes, a conservative Baptist family, flew to California to see Frankel. He started Sawyer on #1 oil, and three months later, the boy was seizure free.

While this should by no means be taken as direct clinical evidence that CBD for weight loss is a tried-and-true remedy for obesity, the studies mentioned above should certainly warrant more investigation into the topic. And to be sure, many folks are already using CBD products to help control their appetite and lose weight. Do a little research online for customer feedback and reviews, and you’ll see what we mean.


CBD interacts with the body’s endocannabinoid system; this system exists to keep our bodies in balance. Most of the time when someone is overweight there is one main culprit that leads to them struggling with weight loss: metabolism. Metabolism and weight loss are very connected because your metabolism is what converts food into energy in the body. It’s also responsible for the body’s ability to burn calories and the rate at which it does so.
When the endocannabinoid system becomes dysregulated, it often becomes overactive and too much fat is being stored, particularly in the intra-abdominal tissue. Cannabidiol is known to regulate the endocannabinoid system as it can restore balance in both directions. Therefore, the study concludes that, along with lifestyle changes cannabis could be a means of fighting obesity.
×