Another study published in 2012 by Farrimond et al. examining the effects of different phytocannabinoids, such as cannabinol (CBN) and CBD, on feeding patterns in rats supports the theory that different cannabinoids modulate CB1 receptors and enhance appetite and metabolism with opposing effects. This study demonstrated that cannabinol increased food intake and body weight gain, while CBD decreased food consumption and weight gain. If your guess is that in this study CBD was also working by “tanning” WAT to BAT, then you are likely spot on.
Another study published in 2012 by Farrimond et al. examining the effects of different phytocannabinoids, such as cannabinol (CBN) and CBD, on feeding patterns in rats supports the theory that different cannabinoids modulate CB1 receptors and enhance appetite and metabolism with opposing effects. This study demonstrated that cannabinol increased food intake and body weight gain, while CBD decreased food consumption and weight gain. If your guess is that in this study CBD was also working by “tanning” WAT to BAT, then you are likely spot on.
The increased activity of the pancreas in an attempt to secrete additional insulin can cause inflammation throughout the gland. That chronic inflammation can actually destroy the beta cells which are the sites that secrete insulin. This downward spiral diminishes the body’s ability to make insulin at all – a dangerous path that can lead to diabetes.
Moreover, the inconsistency (to put it mildly) of the weight loss industry is probably more sketchy and less regulated than the current state of the cannabis industry. Google ‘weight loss scams,’ for instance, and you’ll get 5.76 million search results! There have been some shocking scams over the years, including vibration machines, weight loss pills (containing poisons such as arsenic), and ‘Vision-Dieter Glasses,’ just to name a few.
In 2013, a team of four medical researchers lead by Dr. Elizabeth Penner MD, MPH, carried out a clinical study with over 4,500 participants, called “The Impact of Marijuana Use on Glucose, Insulin, and Insulin Resistance among US Adults”. They concluded: “We found that marijuana use was associated with lower levels of fasting insulin and HOMA-IR, and smaller waist circumference.”
Due to the uniqueness of everyone’s endocannabinoid system, CBD does not affect any two people the same way. There are a host of factors that influence its efficacy, including genetics, previous history of use, general health, weight, ethnicity and so on. Therefore, while one person may find that 15 mg of CBD a day works wonders for suppressing appetite and boosting weight loss, another may require up to 100 mg (or more) in order to achieve the same results (or they may not experience any results at all). 

Frankel also asserts that CBD reduces appetite—the opposite of THC, which triggers hedonic over-eating. I hadn’t read this anywhere, so I invited two friends, Tina and Cha Cha, to try it with me. We would soon be calling ourselves the Ladies Weed Detective Society. We squeezed a few drops of CBD-infused oil under our tongues and waited. An hour later, at the time we’d planned to have dinner, we noticed we weren’t especially hungry. All thoughts of food had been swept away. If this effect were widely known, Tina said, “Cannabis would be legal in twenty minutes.”
To briefly review, the endocannabinoid system (ECS) is a group of specialized fatty acid-based signaling chemicals (think “keys”), their receptors (think “locks”), and the metabolic enzymes that produce and break them down. These endocannabinoid chemical signals act on similar brain and immune cell receptors (CB1 and CB2) using the active compounds found in cannabis – cannabidiol (CBD), and Δ9-tetrahydrocannabinol (THC).
Recent evidence from animal and human studies shows a role for the endocannabinoid system in maintaining energy balance and glucose as well as lipoprotein metabolism, according to a 2009 study. Modulation of this system has resulted in an improvement in a number of important risk factors in clinical trials, including visceral and subcutaneous abdominal adipose tissue, glucose tolerance, dyslipidemia and measures of inflammation.

Due to the uniqueness of everyone’s endocannabinoid system, CBD does not affect any two people the same way. There are a host of factors that influence its efficacy, including genetics, previous history of use, general health, weight, ethnicity and so on. Therefore, while one person may find that 15 mg of CBD a day works wonders for suppressing appetite and boosting weight loss, another may require up to 100 mg (or more) in order to achieve the same results (or they may not experience any results at all).


CBD’s effect on homeostasis is believed to be why those in need of nutrition can experience an appetite increase and those with excess weight can experience an appetite decrease. The reason for this is that CBD is an adaptogen. Referred to by some scientists as “the boy scout molecule” because it always does the right thing in any given situation. The Journal of  Psychopharmacology tested this theory on rats in 2012. The researchers wanted to see how three common cannabinoids, including CBN, CBD, and CBG, affected the appetite of the rats. The study concluded that both CBD and CBG worked to reduce the rat’s appetite.
First of all, we have to bring it to your attention that there are CBD oil scams out there. However, the unscrupulous companies involved in these schemes don’t use high-quality CBD in their products. Pure CBD oil of the highest quality is extracted from industrial hemp via CO2 extraction, and such organizations that use quality oil also include independent third-party lab testing results of their products to guarantee both purity and content.

Due to the uniqueness of everyone’s endocannabinoid system, CBD does not affect any two people the same way. There are a host of factors that influence its efficacy, including genetics, previous history of use, general health, weight, ethnicity and so on. Therefore, while one person may find that 15 mg of CBD a day works wonders for suppressing appetite and boosting weight loss, another may require up to 100 mg (or more) in order to achieve the same results (or they may not experience any results at all).
I’m glad you’ve found help from CBD products, James. I’ve been told by many pros that without any THC, the CBDs are not activated and so you’re essentially not getting hardly any benefit. Or you might need more of the product to get benefit. So I might suggest looking into this and trying a tincture that’s a 20/1 CBD/THC ratio. You won’t feel the THC effects but you’ll get the full benefit the plant has to offer.

CBD and other cannabinoids attach to specific receptors in the body found within what is referred to as the endocannabinoid system. In fact, up until recently, scientists didn’t know that these cannabinoids are actually naturally produced in humans and most animals. Some researchers speculate that an endocannabinoid deficiency may be the cause of many disorders and conditions. When CBD is introduced into the body, it binds to receptor cells called CB1 and CB2 receptors.

Cannabidiol (CBD) is one of over 100 phytocannabinoids found in marijuana and hemp plants. Together with tetrahydrocannabinol (THC), CBD is a cannabinoid intensely investigated for its health properties. Unlike THC, CBD is not psychoactive. This means that when CBD is consumed, it produces no psychological effects, or the controversial “high” marijuana is well known for.

As previously mentioned, CBD and other cannabinoids affect the endocannabinoid system in the body. This system plays a significant role in regulating numerous physiological processes in the body. One of its most vital actions is helping the body to maintain balance. When someone is overweight, generally speaking, it’s not all about overeating or gluttony, but a combination of functions within the human body that are not functioning correctly. Many holistic doctors will agree that our Western diet and the way we treat disease both play a significant role in creating weight gain
×