To briefly review, the endocannabinoid system (ECS) is a group of specialized fatty acid-based signaling chemicals (think “keys”), their receptors (think “locks”), and the metabolic enzymes that produce and break them down. These endocannabinoid chemical signals act on similar brain and immune cell receptors (CB1 and CB2) using the active compounds found in cannabis – cannabidiol (CBD), and Δ9-tetrahydrocannabinol (THC).


Scientists have only scraped the tip of the iceberg so far. The DEA has recently removed  CBD from its list of controlled substances. This significant event paves the way for government-funded grants that will allow some of the best minds in the world study cannabidiol’s effect on the human body. It will be exciting to see what is uncovered in the years to come. For the time being, evidence points to CBD’s use as a valuable tool for losing weight. And because it is safe and readily available in most places (check your own state to be sure), it is a simple way of supplementing your health as you attempt to shed unwanted pounds.
Frankel had rarely tried cannabis until he was 49. He was a partner in one of the most successful practices in West Los Angeles and a clinical professor at UCLA Medical School. He’d been my family’s internist for 15 years, and I found him a skilled diagnostician, who listened carefully, and who cared. He had to quit practicing in 2000, after he’d suffered a disabling back injury, then developed a viral infection of the heart and was told he had six months to live. Some of his cancer and AIDS patients urged him to try cannabis. “They did a reverse intervention,” he said, and a year later, his heart was normal. He can’t be certain how or if cannabis healed his heart. “I’d been depressed and CBD stopped the depression,” he said. “It gave me something to look forward to. My brain was turned on.”
I’m a fan of all Royal CBD products, but as far as weight loss goes, I’d stick to the oil or capsules. Mainly because they offer the full spectrum of cannabinoids, which has been proven superior to isolates in reducing inflammation. The second reason why I wouldn’t include the gummies in my supplementation regime is the sugar content. If you want to lose weight, cutting down on simple sugars is one of the most important steps, so instead, I’d look for more classic formats like oil or capsules.
Frankel puts his hand on his heart. “Imagine the pressure!” he says. A complex soul, whose parents survived the Holocaust, Frankel says that when his patients don’t get better, he’s sad and disappointed, and starts to question if he’s wasting people’s time and money. “But then ten people will get better, and I feel… grateful. It makes me confident I’m on the right road, on the right side of history.”
In 2007, he was investigated by the California Medical Board and in 2008, his license to practice was suspended. He fought this in court, losing his house to pay legal bills, and in 2011, his license was reinstated. During those “hard years,” he said, he hired other doctors to write recommendations for medical marijuana licenses, then Frankel advised the patients how to treat their ailments. “I could have quit and taken a job that paid well, but I kept asking myself, what’s the best thing I can do for my patients?” He thought about what his parents had suffered in Auschwitz. “Why should I crumble because the medical board takes away a piece of paper? I was willing to fight for something I feel is absolutely good—because of its efficacy and lack of side effects.”
Cannabidiol (CBD) is one of over 100 phytocannabinoids found in marijuana and hemp plants. Together with tetrahydrocannabinol (THC), CBD is a cannabinoid intensely investigated for its health properties. Unlike THC, CBD is not psychoactive. This means that when CBD is consumed, it produces no psychological effects, or the controversial “high” marijuana is well known for.
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