To briefly review, the endocannabinoid system (ECS) is a group of specialized fatty acid-based signaling chemicals (think “keys”), their receptors (think “locks”), and the metabolic enzymes that produce and break them down. These endocannabinoid chemical signals act on similar brain and immune cell receptors (CB1 and CB2) using the active compounds found in cannabis – cannabidiol (CBD), and Δ9-tetrahydrocannabinol (THC).
Moreover, Murray Mittleman, an associate professor of medicine at Harvard Medical School, explained to Time Magazine in 2013 that weed users had lower fasting insulin levels and were less resistant to insulin produced by the body. He was referring to research from the National Health and Nutrition Examination Survey, which analyzed 4,600 men and women over a five year period from 2005 to 2010. 48% of them used cannabis at least once in their lives, and 12% were current users.
Another study published in 2012 by Farrimond et al. examining the effects of different phytocannabinoids, such as cannabinol (CBN) and CBD, on feeding patterns in rats supports the theory that different cannabinoids modulate CB1 receptors and enhance appetite and metabolism with opposing effects. This study demonstrated that cannabinol increased food intake and body weight gain, while CBD decreased food consumption and weight gain. If your guess is that in this study CBD was also working by “tanning” WAT to BAT, then you are likely spot on.
On symptoms like pain, CBD has a quick effect, as well as on anxiety etc. But, when you use it regularly and consistently you will notice an improvement in your homeostasis and your overall well-being. Part of that is the improvement of your metabolism, as CBD does not only suppress excessive appetite but it improves your body’s fat burning mechanism.
Due to the uniqueness of everyone’s endocannabinoid system, CBD does not affect any two people the same way. There are a host of factors that influence its efficacy, including genetics, previous history of use, general health, weight, ethnicity and so on. Therefore, while one person may find that 15 mg of CBD a day works wonders for suppressing appetite and boosting weight loss, another may require up to 100 mg (or more) in order to achieve the same results (or they may not experience any results at all).
Before using CBD for weight loss, it is vital to ensure that you are using a quality product, as this has a significant impact on how much it can aid you in losing weight and maintaining what you lose. A company using domestically sourced organic hemp that has been grown in clean soil is your best choice. You also want to make sure third-party lab testing is done on a regular basis and that the extraction methods used in the manufacturing process are clean and solvent-free.