The increased activity of the pancreas in an attempt to secrete additional insulin can cause inflammation throughout the gland. That chronic inflammation can actually destroy the beta cells which are the sites that secrete insulin. This downward spiral diminishes the body’s ability to make insulin at all – a dangerous path that can lead to diabetes.
I use the plain Koi, and mix it with my favorite ejuice, for headaches. If I have a really bad headache, I put a dropper, or two, full under my tongue. Recently, my doctor wouldn’t refill my Vicodin for my pain, so I ordered some full spectrum CBD hemp oil. In Wisconsin, medical marijuana is only prescribed for seizures and marijuana isn’t legal. I hope the full spectrum CBD hemp oil works because I have pain all over, it seems. Fibromyalgia, degenerative joint disorder, and now back problems that cause sciatica. I could stand to lose weight, too.
But, if you are heavily obese you most probably will start with a much higher dosage. In order to find the right dosage for your situation, you can start with a relatively moderate level and, monitor for two weeks, increase, monitor etc. etc. Start with 60mg a day divided into three (or two) takings and see how much weight you lost during a two-week period.

Frankel grew plants, crossed strains, and tried them on friends as well as himself. Working with chemists and professional growers, he developed formulas for whole plant oils, which are manufactured independently and for which he receives no compensation. In 2006, Frankel felt he’d learned enough to open a new practice as a cannabis medical consultant.


Another study published in 2012 by Farrimond et al. examining the effects of different phytocannabinoids, such as cannabinol (CBN) and CBD, on feeding patterns in rats supports the theory that different cannabinoids modulate CB1 receptors and enhance appetite and metabolism with opposing effects. This study demonstrated that cannabinol increased food intake and body weight gain, while CBD decreased food consumption and weight gain. If your guess is that in this study CBD was also working by “tanning” WAT to BAT, then you are likely spot on.
Researchers wrote in 2011 that one of the most important functions of endocannabinoids and CB(1) receptors are to enhance the energy storage conversion into fat and reduce energy expenditure by influencing both lipid and glucose metabolism. Although normally well controlled by hormones etc., the endocannabinoid regulation of energy balance can become dysregulated and contribute to obesity, dyslipidemia and diabetes (type 2).

Alicia Salazar, a New York state board certified health coach, uses CBD with her clients to maximize their health outcomes. “I don’t look at CBD as a magic bullet for weight loss,” she said. “But CBD along with a healthy diet – one that contains healthy fats, whole grains, grass-fed meat and dairy, and plenty of greens, without processed foods and sugar – sets the tone for a healthy weight. And for some, that can naturally include weight loss.”


Due to the uniqueness of everyone’s endocannabinoid system, CBD does not affect any two people the same way. There are a host of factors that influence its efficacy, including genetics, previous history of use, general health, weight, ethnicity and so on. Therefore, while one person may find that 15 mg of CBD a day works wonders for suppressing appetite and boosting weight loss, another may require up to 100 mg (or more) in order to achieve the same results (or they may not experience any results at all).
But, if you are heavily obese you most probably will start with a much higher dosage. In order to find the right dosage for your situation, you can start with a relatively moderate level and, monitor for two weeks, increase, monitor etc. etc. Start with 60mg a day divided into three (or two) takings and see how much weight you lost during a two-week period.
Researchers wrote in 2011 that one of the most important functions of endocannabinoids and CB(1) receptors are to enhance the energy storage conversion into fat and reduce energy expenditure by influencing both lipid and glucose metabolism. Although normally well controlled by hormones etc., the endocannabinoid regulation of energy balance can become dysregulated and contribute to obesity, dyslipidemia and diabetes (type 2).
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I use the plain Koi, and mix it with my favorite ejuice, for headaches. If I have a really bad headache, I put a dropper, or two, full under my tongue. Recently, my doctor wouldn’t refill my Vicodin for my pain, so I ordered some full spectrum CBD hemp oil. In Wisconsin, medical marijuana is only prescribed for seizures and marijuana isn’t legal. I hope the full spectrum CBD hemp oil works because I have pain all over, it seems. Fibromyalgia, degenerative joint disorder, and now back problems that cause sciatica. I could stand to lose weight, too.
While this should by no means be taken as direct clinical evidence that CBD for weight loss is a tried-and-true remedy for obesity, the studies mentioned above should certainly warrant more investigation into the topic. And to be sure, many folks are already using CBD products to help control their appetite and lose weight. Do a little research online for customer feedback and reviews, and you’ll see what we mean.
The previously mentioned study which established improved mitochondrial function with CBD use also observed that CBD stimulates gene expression within white fat cells. This initiates the “browning” of these cells. This mechanism shows promise with converting hard-to-lose white fat into a more easily burnable form. Additionally, researchers found that CBD decreased the rate of new fat cell creation.
Frankel also asserts that CBD reduces appetite—the opposite of THC, which triggers hedonic over-eating. I hadn’t read this anywhere, so I invited two friends, Tina and Cha Cha, to try it with me. We would soon be calling ourselves the Ladies Weed Detective Society. We squeezed a few drops of CBD-infused oil under our tongues and waited. An hour later, at the time we’d planned to have dinner, we noticed we weren’t especially hungry. All thoughts of food had been swept away. If this effect were widely known, Tina said, “Cannabis would be legal in twenty minutes.”
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The CB1 receptors are mostly present in the brain, but some are located throughout your body. These receptors deal with movement and coordination, emotions, thinking, memories, pain, mood, appetite, and other function. The CB2 receptors are mostly in the immune system. They affect pain and inflammation. CBD works in two ways. It attaches itself to these receptors while stimulating the body to produce more cannabinoids on its own naturally. Amazingly, CBD assists the body in learning to heal itself.

Researchers wrote in 2011 that one of the most important functions of endocannabinoids and CB(1) receptors are to enhance the energy storage conversion into fat and reduce energy expenditure by influencing both lipid and glucose metabolism. Although normally well controlled by hormones etc., the endocannabinoid regulation of energy balance can become dysregulated and contribute to obesity, dyslipidemia and diabetes (type 2).
To briefly review, the endocannabinoid system (ECS) is a group of specialized fatty acid-based signaling chemicals (think “keys”), their receptors (think “locks”), and the metabolic enzymes that produce and break them down. These endocannabinoid chemical signals act on similar brain and immune cell receptors (CB1 and CB2) using the active compounds found in cannabis – cannabidiol (CBD), and Δ9-tetrahydrocannabinol (THC).
While overstimulation of the CB1 receptor may lead to symptoms such as high blood pressure and abnormally high cholesterol levels, CBD is a CB1 antagonist, so it is not likely to cause such issues. Furthermore, the World Health Organization has recently issued a global report on CBD, claiming that it has a good safety profile and minimal adverse public health effects.
To briefly review, the endocannabinoid system (ECS) is a group of specialized fatty acid-based signaling chemicals (think “keys”), their receptors (think “locks”), and the metabolic enzymes that produce and break them down. These endocannabinoid chemical signals act on similar brain and immune cell receptors (CB1 and CB2) using the active compounds found in cannabis – cannabidiol (CBD), and Δ9-tetrahydrocannabinol (THC).
Frankel also asserts that CBD reduces appetite—the opposite of THC, which triggers hedonic over-eating. I hadn’t read this anywhere, so I invited two friends, Tina and Cha Cha, to try it with me. We would soon be calling ourselves the Ladies Weed Detective Society. We squeezed a few drops of CBD-infused oil under our tongues and waited. An hour later, at the time we’d planned to have dinner, we noticed we weren’t especially hungry. All thoughts of food had been swept away. If this effect were widely known, Tina said, “Cannabis would be legal in twenty minutes.”
Since I started useing medicinal CBD oil in a vaporizer to treat my fibromialgia pain I have lost 40 pounds of fat without changing anything I’m doing. It controls my hunger and my mood which stopped me from bing eating. It gave me energy to do more without pain as well as clearing up a skin problem I was having that my dermatologist tried every pharmaceutical cream on the market. It took cannabis an illegal product to fix me.
Moreover, the inconsistency (to put it mildly) of the weight loss industry is probably more sketchy and less regulated than the current state of the cannabis industry. Google ‘weight loss scams,’ for instance, and you’ll get 5.76 million search results! There have been some shocking scams over the years, including vibration machines, weight loss pills (containing poisons such as arsenic), and ‘Vision-Dieter Glasses,’ just to name a few.
Cheanné is a freelance writer and blogger. She writes primarily about nutrition, fitness, and mental health. She has diplomas in Personal Nutrition and Weight Loss from Shaw Academy and an Introductory Certificate in Exercise Science from the Health and Fitness Professionals Academy (HFPA). She is also a qualified group fitness instructor. When not writing, she enjoys jamming on her guitar, reading, eating good food, trips to the beach, hiking, and spending time with her family and friends.
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