While overstimulation of the CB1 receptor may lead to symptoms such as high blood pressure and abnormally high cholesterol levels, CBD is a CB1 antagonist, so it is not likely to cause such issues. Furthermore, the World Health Organization has recently issued a global report on CBD, claiming that it has a good safety profile and minimal adverse public health effects.

Frankel also asserts that CBD reduces appetite—the opposite of THC, which triggers hedonic over-eating. I hadn’t read this anywhere, so I invited two friends, Tina and Cha Cha, to try it with me. We would soon be calling ourselves the Ladies Weed Detective Society. We squeezed a few drops of CBD-infused oil under our tongues and waited. An hour later, at the time we’d planned to have dinner, we noticed we weren’t especially hungry. All thoughts of food had been swept away. If this effect were widely known, Tina said, “Cannabis would be legal in twenty minutes.”
On the plus side, there is an earnest desire for people to lose weight, which is why the weight loss industry is worth an astonishing $66 billion! But this staggering number, added to the fact that fewer people are dieting and more are gaining weight, tells us two things: One, that weight loss supplements are fundamentally ineffective; and two, that they are very, very expensive.
Before using CBD for weight loss, it is vital to ensure that you are using a quality product, as this has a significant impact on how much it can aid you in losing weight and maintaining what you lose. A company using domestically sourced organic hemp that has been grown in clean soil is your best choice. You also want to make sure third-party lab testing is done on a regular basis and that the extraction methods used in the manufacturing process are clean and solvent-free.
I’m glad you’ve found help from CBD products, James. I’ve been told by many pros that without any THC, the CBDs are not activated and so you’re essentially not getting hardly any benefit. Or you might need more of the product to get benefit. So I might suggest looking into this and trying a tincture that’s a 20/1 CBD/THC ratio. You won’t feel the THC effects but you’ll get the full benefit the plant has to offer.
The previously mentioned study which established improved mitochondrial function with CBD use also observed that CBD stimulates gene expression within white fat cells. This initiates the “browning” of these cells. This mechanism shows promise with converting hard-to-lose white fat into a more easily burnable form. Additionally, researchers found that CBD decreased the rate of new fat cell creation.
While overstimulation of the CB1 receptor may lead to symptoms such as high blood pressure and abnormally high cholesterol levels, CBD is a CB1 antagonist, so it is not likely to cause such issues. Furthermore, the World Health Organization has recently issued a global report on CBD, claiming that it has a good safety profile and minimal adverse public health effects.
But, if you are heavily obese you most probably will start with a much higher dosage. In order to find the right dosage for your situation, you can start with a relatively moderate level and, monitor for two weeks, increase, monitor etc. etc. Start with 60mg a day divided into three (or two) takings and see how much weight you lost during a two-week period.
Dietary changes are the most important action individuals can choose to get off the roller coaster. But CBD could lend a hand in the process. A 2018 study showed that the cannabinoids THC, CBD and CBN enhance cells’ ability to take up glucose. And they perform even better than metformin, a common pharmaceutical prescribed to lower elevated blood glucose.
Scientists have only scraped the tip of the iceberg so far. The DEA has recently removed  CBD from its list of controlled substances. This significant event paves the way for government-funded grants that will allow some of the best minds in the world study cannabidiol’s effect on the human body. It will be exciting to see what is uncovered in the years to come. For the time being, evidence points to CBD’s use as a valuable tool for losing weight. And because it is safe and readily available in most places (check your own state to be sure), it is a simple way of supplementing your health as you attempt to shed unwanted pounds.
Disclaimer: None of the descriptions/statements made on this website have been evaluated by the FDA (Food and Drug Administration). The supplements and products discussed on this site are not meant to diagnose, heal, cure, mitigate or obviate any diseases. All articles/information on this website are the opinions of their individual writers who do not profess or claim to be medical experts providing medical guidance. This site is strictly for the mission of giving views of the author. You should discuss with your doctor or another adequate health care expert before you start taking any dietary supplements or involve in mental health programs. Different affiliates support this website, and we receive a commission on specific products from our advertisers. Any and all logos, brand names and service marks presented on this site are the registered or unregistered Trademarks of their respective owners.
Another study published in 2012 by Farrimond et al. examining the effects of different phytocannabinoids, such as cannabinol (CBN) and CBD, on feeding patterns in rats supports the theory that different cannabinoids modulate CB1 receptors and enhance appetite and metabolism with opposing effects. This study demonstrated that cannabinol increased food intake and body weight gain, while CBD decreased food consumption and weight gain. If your guess is that in this study CBD was also working by “tanning” WAT to BAT, then you are likely spot on.
Furthermore, a study published in the Journal of Neuroendocrinology has suggested that the ECS is capable of stimulating specific areas of the body involved in metabolism, such as the skeletal muscles and GI tract. This happens due to the presence of anandamide and 2-AG, which are two naturally-occurring compounds in the body that interact with the CB1 and CB2 receptors.
Frankel grew plants, crossed strains, and tried them on friends as well as himself. Working with chemists and professional growers, he developed formulas for whole plant oils, which are manufactured independently and for which he receives no compensation. In 2006, Frankel felt he’d learned enough to open a new practice as a cannabis medical consultant.
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