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In 2013, a team of four medical researchers lead by Dr. Elizabeth Penner MD, MPH, carried out a clinical study with over 4,500 participants, called “The Impact of Marijuana Use on Glucose, Insulin, and Insulin Resistance among US Adults”. They concluded: “We found that marijuana use was associated with lower levels of fasting insulin and HOMA-IR, and smaller waist circumference.”
As previously mentioned, CBD and other cannabinoids affect the endocannabinoid system in the body. This system plays a significant role in regulating numerous physiological processes in the body. One of its most vital actions is helping the body to maintain balance. When someone is overweight, generally speaking, it’s not all about overeating or gluttony, but a combination of functions within the human body that are not functioning correctly. Many holistic doctors will agree that our Western diet and the way we treat disease both play a significant role in creating weight gain
CBD is not often marketed as a weight loss aid, but studies show that it does have the potential for helping people to shed excess pounds. Cannabidiol has been heavily researched by independent organizations, and anecdotal evidence on its benefits for weight loss are widely available. Yet, until recently, the federal government persisted in classifying it as a controlled substance, even though it is nonaddictive, non-psychoactive, is not mood altering, and is safer than aspirin.
While this should by no means be taken as direct clinical evidence that CBD for weight loss is a tried-and-true remedy for obesity, the studies mentioned above should certainly warrant more investigation into the topic. And to be sure, many folks are already using CBD products to help control their appetite and lose weight. Do a little research online for customer feedback and reviews, and you’ll see what we mean.

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First of all, we have to bring it to your attention that there are CBD oil scams out there. However, the unscrupulous companies involved in these schemes don’t use high-quality CBD in their products. Pure CBD oil of the highest quality is extracted from industrial hemp via CO2 extraction, and such organizations that use quality oil also include independent third-party lab testing results of their products to guarantee both purity and content.
In 2013, a team of four medical researchers lead by Dr. Elizabeth Penner MD, MPH, carried out a clinical study with over 4,500 participants, called “The Impact of Marijuana Use on Glucose, Insulin, and Insulin Resistance among US Adults”. They concluded: “We found that marijuana use was associated with lower levels of fasting insulin and HOMA-IR, and smaller waist circumference.”

Frankel also asserts that CBD reduces appetite—the opposite of THC, which triggers hedonic over-eating. I hadn’t read this anywhere, so I invited two friends, Tina and Cha Cha, to try it with me. We would soon be calling ourselves the Ladies Weed Detective Society. We squeezed a few drops of CBD-infused oil under our tongues and waited. An hour later, at the time we’d planned to have dinner, we noticed we weren’t especially hungry. All thoughts of food had been swept away. If this effect were widely known, Tina said, “Cannabis would be legal in twenty minutes.”
Researchers wrote in 2011 that one of the most important functions of endocannabinoids and CB(1) receptors are to enhance the energy storage conversion into fat and reduce energy expenditure by influencing both lipid and glucose metabolism. Although normally well controlled by hormones etc., the endocannabinoid regulation of energy balance can become dysregulated and contribute to obesity, dyslipidemia and diabetes (type 2).
This is likely why CBD is capable of stimulating appetite among people that are in dire need of nutrition (such as cancer patients on chemotherapy), while at the same time suppressing appetite in those who need to lose weight. The active compound helps keep the body in balance, so if you need weight gain it can help you improve your appetite, but if you are overweight, it may be able to help curb your desire to eat.
Moreover, the inconsistency (to put it mildly) of the weight loss industry is probably more sketchy and less regulated than the current state of the cannabis industry. Google ‘weight loss scams,’ for instance, and you’ll get 5.76 million search results! There have been some shocking scams over the years, including vibration machines, weight loss pills (containing poisons such as arsenic), and ‘Vision-Dieter Glasses,’ just to name a few.
While overstimulation of the CB1 receptor may lead to symptoms such as high blood pressure and abnormally high cholesterol levels, CBD is a CB1 antagonist, so it is not likely to cause such issues. Furthermore, the World Health Organization has recently issued a global report on CBD, claiming that it has a good safety profile and minimal adverse public health effects.
Is CBD Legal? Hemp-derived CBD products (with less than 0.3 percent THC) are legal on the federal level, but are still illegal under some state laws. Marijuana-derived CBD products are illegal on the federal level, but are legal under some state laws. Check your state’s laws and those of anywhere you travel. Keep in mind that nonprescription CBD products are not FDA-approved, and may be inaccurately labeled.
Frankel had rarely tried cannabis until he was 49. He was a partner in one of the most successful practices in West Los Angeles and a clinical professor at UCLA Medical School. He’d been my family’s internist for 15 years, and I found him a skilled diagnostician, who listened carefully, and who cared. He had to quit practicing in 2000, after he’d suffered a disabling back injury, then developed a viral infection of the heart and was told he had six months to live. Some of his cancer and AIDS patients urged him to try cannabis. “They did a reverse intervention,” he said, and a year later, his heart was normal. He can’t be certain how or if cannabis healed his heart. “I’d been depressed and CBD stopped the depression,” he said. “It gave me something to look forward to. My brain was turned on.”
The Hemp plant CBD oil is legal in almost all states, as it contains less than 0.3% THC and will not get you high. It is not the same as regular marijuana base CBD that is illegal in a lot of states due to it having a high THC %. I get Pure High Quality Hemp CBD from a really good company that keeps up with and follows the laws of each state. Only state at this time they cannot ship to is NE.
The endocannabinoid system appears to have an essential role in regulating basic human functions like sleep, eating, metabolism, and more. When this system is not functioning correctly, weight gain can occur. CBD helps to restore homeostasis to the cells of the body and can be very useful in reducing fat accumulation and subsequent health risks related to excess body weight.

I asked if he knew why CBD is so broadly effective. Could it be a gigantic, all-purpose placebo? He shook his head. His theory is that it’s an essential nutrient, like vitamins and amino acids, and when there’s a deficiency of CBD, people get sick. Because CBD brings the body into homeostasis, or balance, it can work in two directions: cutting appetite in people who over-eat, and increasing appetite in those who need to eat more.
Interestingly, over-activation of the endocannabinoid system, primarily via CB1 receptor activation, contributes to increased abdominal obesity (i.e., fat gain along the midsection), glucose uptake into adipocytes (fat cells), and insulin resistance in muscle tissue. This “metabolic dysfunction” sets up a vicious cycle whereby further insulin resistance in muscles and the liver increases abdominal obesity and further CB1 over-activation, resulting in greater food-seeking behavior, increased appetite, and increased body fat gain.
On the plus side, there is an earnest desire for people to lose weight, which is why the weight loss industry is worth an astonishing $66 billion! But this staggering number, added to the fact that fewer people are dieting and more are gaining weight, tells us two things: One, that weight loss supplements are fundamentally ineffective; and two, that they are very, very expensive.
Another study published in 2012 by Farrimond et al. examining the effects of different phytocannabinoids, such as cannabinol (CBN) and CBD, on feeding patterns in rats supports the theory that different cannabinoids modulate CB1 receptors and enhance appetite and metabolism with opposing effects. This study demonstrated that cannabinol increased food intake and body weight gain, while CBD decreased food consumption and weight gain. If your guess is that in this study CBD was also working by “tanning” WAT to BAT, then you are likely spot on.

The endocannabinoid system appears to have an essential role in regulating basic human functions like sleep, eating, metabolism, and more. When this system is not functioning correctly, weight gain can occur. CBD helps to restore homeostasis to the cells of the body and can be very useful in reducing fat accumulation and subsequent health risks related to excess body weight.


He did exhaustive research. He found there’d been decades of scientific studies on the effects of THC and CBD on cells and animals, but few trials with humans, because the FDA classifies cannabis and all its components as Schedule 1 drugs, which have “no accepted medical treatment use.” It took Sue Sisley, an Arizona physician, seven years of struggling with bureaucratic hurdles before she received the first FDA approval for a study, just beginning, of marijuana with vets who have PTSD.

CBD’s effect on homeostasis is believed to be why those in need of nutrition can experience an appetite increase and those with excess weight can experience an appetite decrease. The reason for this is that CBD is an adaptogen. Referred to by some scientists as “the boy scout molecule” because it always does the right thing in any given situation. The Journal of  Psychopharmacology tested this theory on rats in 2012. The researchers wanted to see how three common cannabinoids, including CBN, CBD, and CBG, affected the appetite of the rats. The study concluded that both CBD and CBG worked to reduce the rat’s appetite.


Dietary changes are the most important action individuals can choose to get off the roller coaster. But CBD could lend a hand in the process. A 2018 study showed that the cannabinoids THC, CBD and CBN enhance cells’ ability to take up glucose. And they perform even better than metformin, a common pharmaceutical prescribed to lower elevated blood glucose.

 Populum’s CBD oil utilizes a full-spectrum of cannabinoids. It has a subtle orange flavor and contains antioxidants, natural ingredients, and neuroprotectants. It is free from GMOs and gluten. The label shows that this product is made with several oils in addition to hemp oil, including grapeseed, orange, and virgin coconut oils. It also contains stevia extract for a sweet flavor.
Scientists have only scraped the tip of the iceberg so far. The DEA has recently removed  CBD from its list of controlled substances. This significant event paves the way for government-funded grants that will allow some of the best minds in the world study cannabidiol’s effect on the human body. It will be exciting to see what is uncovered in the years to come. For the time being, evidence points to CBD’s use as a valuable tool for losing weight. And because it is safe and readily available in most places (check your own state to be sure), it is a simple way of supplementing your health as you attempt to shed unwanted pounds.
Since I started useing medicinal CBD oil in a vaporizer to treat my fibromialgia pain I have lost 40 pounds of fat without changing anything I’m doing. It controls my hunger and my mood which stopped me from bing eating. It gave me energy to do more without pain as well as clearing up a skin problem I was having that my dermatologist tried every pharmaceutical cream on the market. It took cannabis an illegal product to fix me.
With all of the information inundating the internet about CBD oil, many people are curious, can CBD help with weight loss? A study done in 2012 documented the way that cannabinol and cannabidiol affected the feeding patterns in rats. After dosing rats with CBD, the scientists observed that they ate less; this set the stage for more research to be done to continue to show the weight loss opportunities with CBD. It also brought into light a new use for CBD as an appetite suppressant. In addition to that, a report in India Times in 2016 said that cannabis users show a lower rate of obesity and diabetes. Science has also demonstrated links between the use of cannabis and metabolism for many years.
Another marker of obesity and diabetes includes damage to liver cells. The liver is a major organ in the conversion between stored energy forms and useable energy forms in the body. Overburdening that system, such as with high fructose intake, can have disastrous effects. Inflammation within the liver indicates the onset of dysfunction, and possibly non-alcoholic fatty liver disease.
Before using CBD for weight loss, it is vital to ensure that you are using a quality product, as this has a significant impact on how much it can aid you in losing weight and maintaining what you lose. A company using domestically sourced organic hemp that has been grown in clean soil is your best choice. You also want to make sure third-party lab testing is done on a regular basis and that the extraction methods used in the manufacturing process are clean and solvent-free.
Frankel grew plants, crossed strains, and tried them on friends as well as himself. Working with chemists and professional growers, he developed formulas for whole plant oils, which are manufactured independently and for which he receives no compensation. In 2006, Frankel felt he’d learned enough to open a new practice as a cannabis medical consultant.
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