Cannabidiol (CBD) is one of over 100 phytocannabinoids found in marijuana and hemp plants. Together with tetrahydrocannabinol (THC), CBD is a cannabinoid intensely investigated for its health properties. Unlike THC, CBD is not psychoactive. This means that when CBD is consumed, it produces no psychological effects, or the controversial “high” marijuana is well known for.
Interestingly, over-activation of the endocannabinoid system, primarily via CB1 receptor activation, contributes to increased abdominal obesity (i.e., fat gain along the midsection), glucose uptake into adipocytes (fat cells), and insulin resistance in muscle tissue. This “metabolic dysfunction” sets up a vicious cycle whereby further insulin resistance in muscles and the liver increases abdominal obesity and further CB1 over-activation, resulting in greater food-seeking behavior, increased appetite, and increased body fat gain.
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Frankel puts his hand on his heart. “Imagine the pressure!” he says. A complex soul, whose parents survived the Holocaust, Frankel says that when his patients don’t get better, he’s sad and disappointed, and starts to question if he’s wasting people’s time and money. “But then ten people will get better, and I feel… grateful. It makes me confident I’m on the right road, on the right side of history.”
Another study published in 2012 by Farrimond et al. examining the effects of different phytocannabinoids, such as cannabinol (CBN) and CBD, on feeding patterns in rats supports the theory that different cannabinoids modulate CB1 receptors and enhance appetite and metabolism with opposing effects. This study demonstrated that cannabinol increased food intake and body weight gain, while CBD decreased food consumption and weight gain. If your guess is that in this study CBD was also working by “tanning” WAT to BAT, then you are likely spot on.
Utah company Kanibi is a new player on the CBD scene. They bring scientific precision and a focus on performance to their products. The company offers a pretty limited product selection: an oil tincture and a sports cream. But they lack in variety, they make up for in quality. Every product gets double lab tested, so consumers know exactly how much CBD they’re getting from their purchase.
Correcting a calorie excess with a calorie deficit sometimes works for weight loss, but it can be difficult. First of all, reducing calories leaves people feeling hungry, which can be incredibly uncomfortable. Second of all, weight gain can cause changes to hormone levels and balance, metabolic patterns, inflammation status, and balance within the endocannabinoid system.
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