Cannabidiol (CBD) is one of over 100 phytocannabinoids found in marijuana and hemp plants. Together with tetrahydrocannabinol (THC), CBD is a cannabinoid intensely investigated for its health properties. Unlike THC, CBD is not psychoactive. This means that when CBD is consumed, it produces no psychological effects, or the controversial “high” marijuana is well known for.
During a day at his office, I saw three patients who’d had success with CBD. The first was Sawyer Maddox, five, from Atlanta, who’d been diagnosed at three with a rare form of epilepsy, Doose Syndrome, which is resistant to medication. He was having more than 200 seizures a day, where he’d drop face first on the floor. His parents fitted him with a catcher’s mask for protection, and carpeted their home with foam to cushion his falls. The pediatric neurologist they saw in Atlanta gave him meds that made things worse. Desperate, the Maddoxes, a conservative Baptist family, flew to California to see Frankel. He started Sawyer on #1 oil, and three months later, the boy was seizure free.
CBD’s effect on homeostasis is believed to be why those in need of nutrition can experience an appetite increase and those with excess weight can experience an appetite decrease. The reason for this is that CBD is an adaptogen. Referred to by some scientists as “the boy scout molecule” because it always does the right thing in any given situation. The Journal of  Psychopharmacology tested this theory on rats in 2012. The researchers wanted to see how three common cannabinoids, including CBN, CBD, and CBG, affected the appetite of the rats. The study concluded that both CBD and CBG worked to reduce the rat’s appetite.

While overstimulation of the CB1 receptor may lead to symptoms such as high blood pressure and abnormally high cholesterol levels, CBD is a CB1 antagonist, so it is not likely to cause such issues. Furthermore, the World Health Organization has recently issued a global report on CBD, claiming that it has a good safety profile and minimal adverse public health effects.


I’m a fan of all Royal CBD products, but as far as weight loss goes, I’d stick to the oil or capsules. Mainly because they offer the full spectrum of cannabinoids, which has been proven superior to isolates in reducing inflammation. The second reason why I wouldn’t include the gummies in my supplementation regime is the sugar content. If you want to lose weight, cutting down on simple sugars is one of the most important steps, so instead, I’d look for more classic formats like oil or capsules.
Hemplucid uses domestically sourced full-spectrum CBD to make this tincture. It includes a medium-chain triglyceride carrier MCT oil as part of the formula. This product contains terpenes and nearly undetectable levels of THC. The ingredients are all-natural, and they come from hemp plants that are bred for almost ten years to ensure a high level of cannabinoids. This product is certified as organic, and it does not contain GMOs.

Bluebird Botanicals is a liquid extract oil blend. It contains a variety of hemp extracts. This formulation includes both CBDa (non-decarboxylated) and CBD (decarboxylated) forms of cannabinoids using a 1:1 ratio. The hemp extract is steam distilled which ensures that all the beneficial terpenes remain intact. It also contains a variety of ketones, aldehydes, and organic extra virgin olive oil.


Bluebird Botanicals is a liquid extract oil blend. It contains a variety of hemp extracts. This formulation includes both CBDa (non-decarboxylated) and CBD (decarboxylated) forms of cannabinoids using a 1:1 ratio. The hemp extract is steam distilled which ensures that all the beneficial terpenes remain intact. It also contains a variety of ketones, aldehydes, and organic extra virgin olive oil.
Frankel puts his hand on his heart. “Imagine the pressure!” he says. A complex soul, whose parents survived the Holocaust, Frankel says that when his patients don’t get better, he’s sad and disappointed, and starts to question if he’s wasting people’s time and money. “But then ten people will get better, and I feel… grateful. It makes me confident I’m on the right road, on the right side of history.”
On the plus side, there is an earnest desire for people to lose weight, which is why the weight loss industry is worth an astonishing $66 billion! But this staggering number, added to the fact that fewer people are dieting and more are gaining weight, tells us two things: One, that weight loss supplements are fundamentally ineffective; and two, that they are very, very expensive.
Dietary changes are the most important action individuals can choose to get off the roller coaster. But CBD could lend a hand in the process. A 2018 study showed that the cannabinoids THC, CBD and CBN enhance cells’ ability to take up glucose. And they perform even better than metformin, a common pharmaceutical prescribed to lower elevated blood glucose.

I asked if he knew why CBD is so broadly effective. Could it be a gigantic, all-purpose placebo? He shook his head. His theory is that it’s an essential nutrient, like vitamins and amino acids, and when there’s a deficiency of CBD, people get sick. Because CBD brings the body into homeostasis, or balance, it can work in two directions: cutting appetite in people who over-eat, and increasing appetite in those who need to eat more.
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