Frankel grew plants, crossed strains, and tried them on friends as well as himself. Working with chemists and professional growers, he developed formulas for whole plant oils, which are manufactured independently and for which he receives no compensation. In 2006, Frankel felt he’d learned enough to open a new practice as a cannabis medical consultant.
I asked if he knew why CBD is so broadly effective. Could it be a gigantic, all-purpose placebo? He shook his head. His theory is that it’s an essential nutrient, like vitamins and amino acids, and when there’s a deficiency of CBD, people get sick. Because CBD brings the body into homeostasis, or balance, it can work in two directions: cutting appetite in people who over-eat, and increasing appetite in those who need to eat more.
While overstimulation of the CB1 receptor may lead to symptoms such as high blood pressure and abnormally high cholesterol levels, CBD is a CB1 antagonist, so it is not likely to cause such issues. Furthermore, the World Health Organization has recently issued a global report on CBD, claiming that it has a good safety profile and minimal adverse public health effects.
Furthermore, a study published in the Journal of Neuroendocrinology has suggested that the ECS is capable of stimulating specific areas of the body involved in metabolism, such as the skeletal muscles and GI tract. This happens due to the presence of anandamide and 2-AG, which are two naturally-occurring compounds in the body that interact with the CB1 and CB2 receptors.
 Populum’s CBD oil utilizes a full-spectrum of cannabinoids. It has a subtle orange flavor and contains antioxidants, natural ingredients, and neuroprotectants. It is free from GMOs and gluten. The label shows that this product is made with several oils in addition to hemp oil, including grapeseed, orange, and virgin coconut oils. It also contains stevia extract for a sweet flavor.
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